Air Portugal operate flights from Lisbon to Sao Tome each Thursday evening, returning from Sao Tome on a Friday morning. There are connections from London Heathrow and most other European airports.

TAAG - Air Angola operate a direct flight between the capital of Cape Verde- Santiago and Sao Tome, making Cape Verde and Sao Tome the perfect twin centre.

It is also possible to create open jaw tickets with Air Portugal meaning you can fly from London via Lisbon to Sal or Santiago in Cape Verde and fly back from Sao Tome via Lisbon to London with a one way flight between Cape Verde and Sao Tome with TAAG.

Outbound
Thursday London Heathrow to Lisbon 19:50-22:30 Thursday Lisbon to Sao Tome 23:35-05:35	from £769.00 per person
Inbound
Fridays Sao Tome to Lisbon 07:05-13:05 Fridays Lisbon to London Heathrow 14:40-17:30
Outbound
Fridays Santiago, Cape Verde to Sao Tome 09:00-14:45	from £349.00 per person
Inbound
Thursdays Sao Tome to Santiago, Cape Verde 13:15-17:00

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